The A169 has now fully re-opened following an accident this morning.
The two cars involved were a Vauxhall Corsa and a Renault Megane.
The driver of the Corsa, a woman in her twenties, suffered shock and was taken to York District Hospital to be checked over. The passenger of the Corsa, a man in his twenties, was also taken to York District Hospital with minor injuries.
The driver of the Megane, a man in his forties, did not sustain injuries but was taken to Scarborough Hospital to be checked over.
A woman in her eighties who was a rear seat passenger in the Megane sustained serious injuries and was air lifted to James Cook Hospital, where she is in a critical condition.
Another passenger, a woman also in her eighties, was taken to Scarborough hospital with serious, but not believed to be life threatening, injuries.
At the time of the collision, the Corsa was travelling North and the Megane was travelling South.
Officers are appealing for anyone who witnessed the collision, or who saw either vehicle prior to the collision,which took place around 11.30am to get in touch.
Dial 101, press 1 and pass information onto the force control room.
Please quote reference number NYP-18082016-0179 when passing on information.
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